Brian G. Pettyjohn holds a solid educational background, having graduated from Sussex Central High School and the University of Delaware. He began his political career by winning a seat on the Georgetown town council, followed by a mayoral victory in Georgetown. Pettyjohn has served multiple terms in the Delaware State Senate, marked by significant electoral success and involvement in various legislative committees. He has taken leadership roles within the Republican party and has been active in multiple task forces and advisory boards focused on education, finance, and public safety. Pettyjohn has also been involved in community organizations, demonstrating a commitment to local issues.

Brian G. Pettyjohn's political career is marked by a blend of traditional conservatism with surprising policy stances. He has vocally opposed gun control laws, yet his involvement in a legal incident regarding firearms on an airplane adds a layer of complexity to his stance. Notably, Pettyjohn reversed his support for the Delaware Equal Rights Amendment, raising questions about his evolving views on women's rights. His legislative initiatives, such as funding for trade schools, suggest a focus on practical skill development over traditional education paths. Pettyjohn's extensive committee assignments and leadership roles indicate a deep engagement with legislative processes, yet his willingness to challenge party norms hints at an ideologically agile approach.